Chemical Exposure-Related Metabolism Alterations in Mammalian CellCultures

Chemical Exposure-Related Metabolism Alterations in Mammalian CellCultures

Twin Results of Non-Coding RNAs (ncRNAs) in Most cancers Stem Cell Biology

The identification of most cancers stem cells (CSCs) as initiators of carcinogenesis has revolutionized the period of most cancers analysis and our notion for the illness remedy choices. Further CSC options, together with self-renewal and migratory and invasive capabilities, have additional justified these cells as putative diagnostic, prognostic, and therapeutic targets.

Given the CSC plasticity, the identification of CSC-related biomarkers has been a severe burden in CSC characterization and therapeutic focusing on. Over the previous a long time, a compelling quantity of proof has demonstrated vital regulatory capabilities of non-coding RNAs (ncRNAs) on the unique options of CSCs.

We now know that ncRNAs might intervene with signaling pathways, important for CSC phenotype upkeep, equivalent to Notch, Wnt, and Hedgehog. Right here, we talk about the multifaceted contribution of microRNAs (miRNAs), lengthy non-coding RNAs (lncRNAs) and round RNAs (circRNAs), as consultant ncRNA lessons, in sustaining the CSC-like traits, in addition to the underlying molecular mechanisms of their motion in varied CSC sorts. We additional talk about using CSC-related ncRNAs as putative biomarkers of excessive diagnostic, prognostic, and therapeutic worth. 

Metabolomic Approaches to Examine Chemical Publicity-Associated Metabolism Alterations in Mammalian CellCultures

Natural organisms are constantly uncovered to an immense repertoire of molecules that cowl environmental or food-derived molecules and medicines, triggering a gradual motion of stimuli-dependent variations.

  • The number of these chemical substances along with their concentrations contribute to the multiplicity of induced outcomes, along with activation, stimulation, or inhibition of physiological processes and toxicity. Metabolism, as a result of the foremost phenotype and manifestation of life, has confirmed to be immensely delicate and intensely adaptive to chemical stimuli.
  • Subsequently, studying the impression of endo- or xenobiotics over cellular metabolism delivers priceless info to apprehend potential cellular train of explicit particular person molecules and think about their acute or energy benefits and toxicity.
  • The occasion of latest metabolomics utilized sciences akin to mass spectrometry or nuclear magnetic resonance spectroscopy now provides unprecedented choices for the speedy and setting pleasant willpower of metabolic profiles of cells and additional difficult natural strategies.
  • Blended with the availability of well-established cell custom methods, these analytical methods appear fully suited to seek out out the natural train and estimate the constructive and adversarial outcomes of chemical substances in numerous cell types and fashions, even at hardly detectable concentrations.

 

  • Metabolic phenotypes can be estimated from studying intracellular metabolites at homeostasis in vivo, whereas in vitro cell cultures current further entry to metabolites exchanged with progress media.
  • This textual content discusses analytical choices on the market for metabolic phenotyping of cell custom metabolism along with the general metabolomics workflow applicable for testing the natural train of molecular compounds.
  • We emphasize how metabolic profiling of cell supernatants and intracellular extracts can ship priceless and complementary insights for evaluating the implications of xenobiotics on cellular metabolism. We phrase that the concepts and techniques talked about primarily for xenobiotics publicity are extensively related to drug testing on the entire, along with endobiotics that cowl energetic metabolites, nutritional vitamins, peptides and proteins, cytokines, hormones, dietary nutritional vitamins, and so forth.
stemcelldocs
stemcelldocs

Plasminogen, Human Plasma

7549-1
EUR 283

Human Plasminogen Protein

abx060920-1mg 1 mg
EUR 384
  • Shipped within 5-10 working days.

Recombinant human Plasminogen

P1582 100ug Ask for price
  • Uniprot ID: P00747
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for human Plasminogen

Human Lys-Plasminogen Antibody

33130-05111 150 ug
EUR 261

Human Plasminogen (PLG) Antibody

11491-05011 150 ug
EUR 217

Human Plasminogen ELISA Kit

E-80PMG 1 x 96 well plate
EUR 370

Human Plasminogen ELISA kit

E01P0127-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A sandwich ELISA for quantitative measurement of Human Plasminogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Plasminogen ELISA kit

E01P0127-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human Plasminogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Plasminogen ELISA kit

E01P0127-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human Plasminogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Plasminogen (Plg) Protein

20-abx068558
  • EUR 356.00
  • EUR 217.00
  • EUR 968.00
  • EUR 439.00
  • EUR 286.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Human Plasminogen (Plg) Protein

20-abx068560
  • EUR 356.00
  • EUR 217.00
  • EUR 968.00
  • EUR 439.00
  • EUR 286.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Human Plasminogen (Plg) Protein

20-abx651557
  • EUR 787.00
  • EUR 300.00
  • EUR 2486.00
  • EUR 940.00
  • EUR 551.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Human plasminogen ELISA kit

LF-EK0157 1×96T
EUR 429

Human Plasminogen ELISA Kit

STA-393 96 assays
EUR 676
Description: Cell Biolabs? Human Plasminogen ELISA Kit is an enzyme immunoassay developed for the detection and quantitation of human plasminogen in plasma, serum or other biological fluid samples.  The kit has a detection sensitivity limit of 150 pg/mL human plasminogen.  Each kit provides sufficient reagents to perform up to 96 assays including standard curve and unknown samples. 

Plasminogen protein

30-AP27 1 mg
EUR 294
Description: Purified native Human Plasminogen protein

Plasminogen antibody

20C-CR8063SP 1 mg
EUR 165
Description: Sheep polyclonal Plasminogen antibody

Plasminogen antibody

20R-1359 5 mg
EUR 225
Description: Goat polyclonal Plasminogen antibody

Plasminogen antibody

20R-1360 5 mg
EUR 225
Description: Sheep polyclonal Plasminogen antibody

Plasminogen antibody

20R-PG001 500 ug
EUR 435
Description: Goat polyclonal Plasminogen antibody

Plasminogen antibody

70R-10577 500 ug
EUR 358
Description: Affinity purified goat polyclonal Plasminogen antibody

Plasminogen antibody

70R-10578 500 ug
EUR 358
Description: Affinity purified sheep polyclonal Plasminogen antibody

Plasminogen Antibody

7014-100
EUR 338

Plasminogen Antibody

7014-30T
EUR 146

Plasminogen antibody

10R-P132a 1 mg
EUR 359
Description: Mouse monoclonal Plasminogen antibody

Plasminogen antibody

10C-CR6065M1 100 ug
EUR 136
Description: Mouse monoclonal Plasminogen antibody

Plasminogen antibody

10-7945 1 mg
EUR 358
Description: Mouse monoclonal Plasminogen antibody

Plasminogen antibody

20-S4603GND1-D0 10 ml
EUR 241
Description: Goat polyclonal Plasminogen antibody

Plasminogen antibody

20-S4611G000-S0 10 ml
EUR 111
Description: Goat polyclonal Plasminogen antibody

Plasminogen antibody

20-S4611G000-V0 10 ml
EUR 133
Description: Goat polyclonal Plasminogen antibody

Plasminogen antibody

20-S4611GOOO-S4 10 ml
EUR 138
Description: Goat polyclonal Human Plasminogen antibody

Plasminogen antibody

10R-8453 100 ul
EUR 393
Description: Mouse monoclonal Plasminogen antibody

Plasminogen antibody

10R-8472 100 ul
EUR 393
Description: Mouse monoclonal Plasminogen antibody

Plasminogen antibody

10R-8473 100 ul
EUR 393
Description: Mouse monoclonal Plasminogen antibody

Plasminogen antibody

70R-7562 1 mg
EUR 285
Description: Affinity purified Goat polyclonal Plasminogen antibody

Plasminogen antibody

70R-5384 50 ug
EUR 467
Description: Rabbit polyclonal Plasminogen antibody raised against the middle region of PLG

anti-Plasminogen

YF-PA13815 50 ul
EUR 363
Description: Mouse polyclonal to Plasminogen

anti-Plasminogen

YF-PA13816 50 ug
EUR 363
Description: Mouse polyclonal to Plasminogen

anti-Plasminogen

YF-PA13817 100 ug
EUR 403
Description: Rabbit polyclonal to Plasminogen

Human Plasminogen,Plg ELISA Kit

201-12-1127 96 tests
EUR 440
  • This Plasminogen ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Plasminogen Activator Inhibitor-1

7-03571 2µg Ask for price

Human Plasminogen Activator Inhibitor-1

7-03572 10µg Ask for price

Human Plasminogen Activator Inhibitor-1

7-03573 1mg Ask for price

Recombinant Human Tissue Plasminogen Activator

7-03667 20µg Ask for price

Recombinant Human Tissue Plasminogen Activator

7-03668 100µg Ask for price

Recombinant Human Tissue Plasminogen Activator

7-03669 1mg Ask for price

Human Plasminogen (Plg) ELISA Kit

DLR-Plg-Hu-48T 48T
EUR 441
  • Should the Human Plasminogen (Plg) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Plasminogen (Plg) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Plasminogen (Plg) ELISA Kit

DLR-Plg-Hu-96T 96T
EUR 570
  • Should the Human Plasminogen (Plg) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Plasminogen (Plg) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Plasminogen (PLG) ELISA Kit

DEIA9387V2 96T
EUR 772
Description: Plasminogen is a single chain glycoprotein zymogen that is synthesized in the liver and circulated in plasma with a molecular weight of 90 kDa. The N- terminal portion of the molecule is made up of five kringle domains that bind to fibrin. The native molecule has an amino-terminal glutamic acid, known as glu-plasminogen, but this can undergo proteolytic cleavage by plasmin to lys- plasminogen (1). The inactive proenzyme plasminogen is converted to the active enzyme plasmin that ultimately digests fibrin. Tissue-type plasminogen activator (tPA) or urokinase-type plasminogen activator (uPA) catalyzes the activation of plasminogen, while plasminogen activator inhibitors (PAIs) inhibits the activation (2).

Human Plasminogen activator ELISA kit

E01P0684-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Plasminogen activator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Plasminogen activator ELISA kit

E01P0684-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Plasminogen activator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Plasminogen activator ELISA kit

E01P0684-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Plasminogen activator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Fibrinogen (plasminogen depleted), Human Plasma

7692-1
EUR 294

Human Plasminogen (PLG) CLIA Kit

20-abx190157
  • EUR 7911.00
  • EUR 4215.00
  • EUR 973.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Human Plasminogen (Plg) CLIA Kit

abx197477-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Human Plasminogen (PLG) ELISA Kit

20-abx152771
  • EUR 6173.00
  • EUR 3291.00
  • EUR 770.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Human Plasminogen (PLG) ELISA Kit

abx253552-96tests 96 tests
EUR 754
  • Shipped within 5-12 working days.

Human plasminogen activator Elisa Kit

ELA-E1285h 96 Tests
EUR 824

Human PLG/ Plasminogen ELISA Kit

E1966Hu 1 Kit
EUR 537

Plasminogen (PLG) (Human) ELISA Kit

E4641-100
EUR 805

Human PLG(Plasminogen) ELISA Kit

EH0584 96T
EUR 524.1
  • Detection range: 78.125-5000 pg/ml
  • Uniprot ID: P00747
  • Alias: PLG(plasminogen)/Plg/plasmin
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Human Plasminogen, PLG ELISA KIT

ELI-04090h 96 Tests
EUR 824

Human Plasminogen,Plg ELISA Kit

CN-04049H1 96T
EUR 438

Human Plasminogen,Plg ELISA Kit

CN-04049H2 48T
EUR 289

Human Plasminogen, Plg ELISA Kit

CSB-E09177h-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitative competitive ELISA kit for measuring Human Plasminogen, Plg in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Plasminogen, Plg ELISA Kit

1-CSB-E09177h
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitative competitive ELISA kit for measuring Human Plasminogen, Plg in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Plasminogen (PLG) ELISA Kit

abx573797-96tests 96 tests
EUR 754
  • Shipped within 5-12 working days.

Human Plasminogen (Plg) Protein (Active)

20-abx655799
  • EUR 551.00
  • EUR 258.00
  • EUR 1609.00
  • EUR 648.00
  • EUR 411.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Human Plasminogen (Plg) Protein (Active)

20-abx655800
  • EUR 551.00
  • EUR 258.00
  • EUR 1609.00
  • EUR 648.00
  • EUR 411.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Human Plasminogen(Plg)ELISA Kit

GA-E1143HM-48T 48T
EUR 289

Human Plasminogen(Plg)ELISA Kit

GA-E1143HM-96T 96T
EUR 466

Human plasminogen ELISA kit (4X96T)

LF-EK0158 4×96T
EUR 2045

Human plasminogen ELISA kit (10X96T)

LF-EK0159 10×96T
EUR 4484

Human plasminogen ELISA kit (20X96T)

LF-EK0160 20×96T
EUR 7808

Plasminogen (Plg) Polyclonal Antibody (Human)

4-PAB236Hu02
  • EUR 217.00
  • EUR 2048.00
  • EUR 520.00
  • EUR 268.00
  • EUR 201.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Plg (Asn79~Pro466)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Plasminogen (Plg)

Human Plasminogen(Plg)ELISA Kit

QY-E00915 96T
EUR 361

Human Plasminogen ELISA Kit (Plg)

RK02100 96 Tests
EUR 521

Human Plasminogen (Plg)CLIA Kit

SCB236Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Plasminogen (Plg) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Plasminogen (Plg) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Plasminogen (Plg)CLIA Kit

SCB236Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Plasminogen (Plg) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Plasminogen (Plg) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Plasminogen (Plg)CLIA Kit

SCB236Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Plasminogen (Plg) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Plasminogen (Plg) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Plasminogen (Plg)CLIA Kit

SCB236Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Plasminogen (Plg) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Plasminogen (Plg) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Plasminogen (Plg) CLIA Kit

4-SCB236Hu
  • EUR 5698.00
  • EUR 3061.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Plasminogen Clia kit. Alternative names of the recognized antigen: PL
  • Plasmin
  • Activation peptide
  • Angiostatin
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Plasminogen (Plg)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Human Plasminogen (Plg) ELISA Kit

SEB236Hu-10x96wellstestplate 10x96-wells test plate
EUR 3815.2
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Plasminogen (Plg) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Plasminogen (Plg) in plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Plasminogen (Plg) ELISA Kit

SEB236Hu-1x48wellstestplate 1x48-wells test plate
EUR 401.84
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Plasminogen (Plg) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Plasminogen (Plg) in plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Plasminogen (Plg) ELISA Kit

SEB236Hu-1x96wellstestplate 1x96-wells test plate
EUR 531.2
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Plasminogen (Plg) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Plasminogen (Plg) in plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Plasminogen (Plg) ELISA Kit

SEB236Hu-5x96wellstestplate 5x96-wells test plate
EUR 2090.4
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Plasminogen (Plg) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Plasminogen (Plg) in plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Plasminogen (Plg) ELISA Kit

4-SEB236Hu
  • EUR 3866.00
  • EUR 2041.00
  • EUR 532.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Plasminogen elisa. Alternative names of the recognized antigen: PL
  • Plasmin
  • Activation peptide
  • Angiostatin
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Plasminogen (Plg) in samples from plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Plasminogen Activator Inhibitor-1

RP-1471 10 ug
EUR 286

Human Plasminogen (Plg) ELISA Kit

RDR-Plg-Hu-48Tests 48 Tests
EUR 455

Human Plasminogen (Plg) ELISA Kit

RDR-Plg-Hu-96Tests 96 Tests
EUR 629

Human Plasminogen (Plg) ELISA Kit

RD-Plg-Hu-48Tests 48 Tests
EUR 436

Human Plasminogen (Plg) ELISA Kit

RD-Plg-Hu-96Tests 96 Tests
EUR 601

Plasminogen ELISA Kit (Human) (OKIA00080)

OKIA00080 96 Wells
EUR 505
Description: Description of target: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 2.114 ng/ml

Lys-Plasminogen protein

30C-CP2108U 1 mg
EUR 327
Description: Purified native Human Lys-Plasminogen protein

Plasminogen Blocking Peptide

33R-5066 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PLG antibody, catalog no. 70R-5384

Plasminogen antibody (HRP)

60R-1007 100 ug
EUR 325
Description: Goat polyclonal Plasminogen antibody (HRP) conjugated

Plasminogen Antibody Pair

55R-1013 5 plates
EUR 677
Description: Plasminogen Matched Pair antibody Set for ELISA

Plasminogen ELISA kit

55R-1883 1 kit
EUR 743
Description: ELISA kit for the detection of Plasminogen in the research laboratory

Active Plasminogen (Plg)

4-APB236Hu01
  • EUR 390.30
  • EUR 207.00
  • EUR 1188.64
  • EUR 462.88
  • EUR 825.76
  • EUR 324.00
  • EUR 2821.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P00747
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): Inquire
  • Isoelectric Point: 6.7
Description: Recombinant Human Active Plasminogen (Plg) expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Wanting again and searching ahead: contributions of electron microscopy to the structural cell biology of gametes and fertilization 

Mammalian gametes-the sperm and the egg-represent reverse extremes of mobile group and scale. Finding out the ultrastructure of gametes is essential to understanding their interactions, and methods to manipulate them with the intention to both encourage or stop their union. Right here, we survey the outstanding electron microscopy (EM) methods, with an emphasis on concerns for making use of them to check mammalian gametes.

We overview how standard EM has supplied vital perception into gamete ultrastructure, but in addition how the cruel pattern preparation strategies required preclude understanding at a very molecular degree. We current latest developments in cryo-electron tomography that present a possibility to picture cells in a near-native state and at unprecedented ranges of element.

New and rising mobile EM methods are poised to rekindle exploration of elementary questions in mammalian replica, particularly phenomena that contain complicated membrane remodelling and protein reorganization. These strategies can even permit novel traces of enquiry into issues of sensible significance, equivalent to investigating unexplained causes of human infertility and enhancing assisted reproductive applied sciences for biodiversity conservation.

Transcriptomic and Proteomic Evaluation of Clear Cell Foci (CCF) within the Human Non-Cirrhotic Liver Identifies A number of Differentially Expressed Genes and Proteins with Features in Most cancers Cell Biology and Glycogen Metabolism 

Clear cell foci (CCF) of the liver are thought-about to be pre-neoplastic lesions of hepatocellular adenomas and carcinomas. They’re hallmarked by glycogen overload and activation of AKT (v-akt murine thymoma viral oncogene homolog)/mTOR (mammalian goal of rapamycin)-signaling. Right here, we report the transcriptome and proteome of CCF extracted from human liver biopsies by laser seize microdissection.

We discovered 14 genes and 22 proteins differentially expressed in CCF and nearly all of these had been expressed at decrease ranges in CCF. Utilizing immunohistochemistry, the diminished expressions of STBD1 (starch-binding domain-containing protein 1), USP28 (ubiquitin-specific peptidase 28), monad/WDR92 (WD repeat area 92), CYB5B (Cytochrome b5 kind B), and HSPE1 (10 kDa warmth shock protein, mitochondrial) had been validated in CCF in unbiased specimens.

Knockout of Stbd1, the gene coding for Starch-binding domain-containing protein 1, in mice didn’t have a major impact on liver glycogen ranges, indicating that extra elements are required for glycogen overload in CCFUsp28 knockout mice didn’t present adjustments in glycogen storage in diethylnitrosamine-induced liver carcinoma, demonstrating that CCF are distinct from any such most cancers mannequin, regardless of the decreased USP28 expression.

Furthermore, our information signifies that decreased USP28 expression is a novel issue contributing to the pre-neoplastic character of CCF. In abstract, our work identifies a number of novel and surprising candidates which might be differentially expressed in CCF and which have capabilities in glycogen metabolism and tumorigenesis.

pBABE-Puro Retroviral Vector

RTV-001-PURO 10 ?g
EUR 566
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pBABE-Neo-hTERT Retroviral Vector

RTV-005 100 µL
EUR 717
Description: Use this gene-specific construct for downstream recombinant retroviral packaging

pBABE-Hygro-hTERT Retroviral Vector

RTV-007 100 µL
EUR 717
Description: Use this gene-specific construct for downstream recombinant retroviral packaging

pBABE-Hygro Retroviral Vector

RTV-001-HYGRO 10 ?g
EUR 566
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pBABE-GFP Retroviral Vector

RTV-002 10 ?g
EUR 717
Description: Use this gene-specific construct for downstream recombinant retroviral packaging

pBABE-Neo Retroviral Vector

RTV-003 100 µL
EUR 566
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pBABE-Zeo Retroviral Vector

RTV-004 100 µL
EUR 566
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pBABE- neo- hTERT

PVT10354 2 ug
EUR 301

pBABE-hygro-hTERT

PVT17568 2 ug
EUR 341

hTERT (CMV, Puro) lentivirus

LVP1130-Puro 1x107 IFU/ml x 200ul
EUR 349
Description: Premade lentivirus expressing human TERT gene under suCMV promoter, containing Puromycin marker.

hTERT (EF1a, Puro) lentivirus

LVP1131-Puro 1x107 IFU/ml x 200ul
EUR 349
Description: Premade lentivirus expressing human TERT gene under EF1a promoter, containing Puromycin marker.

hTERT (CMV, Puro) lentivirus in PBS

LVP1130-Puro-PBS 1x108 IFU/ml x 200ul
EUR 710
Description: Concentrated lentivirus in PBS, expressing human TERT gene under suCMV promoter, containing Puromycin marker.

hTERT (EF1a, Puro) lentivirus in PBS

LVP1131-Puro-PBS 1x108 IFU/ml x 200ul
EUR 710
Description: Concentrated lentivirus in PBS, expressing human TERT gene under EF1a promoter, containing Puromycin marker.

pBABE- Puro

PVT11054 2 ug
EUR 301

pMXs-Puro Retroviral Vector

RTV-012 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMYs-Puro Retroviral Vector

RTV-024 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMCs-Puro Retroviral Vector

RTV-041 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-IRES-Puro Retroviral Vector

RTV-014 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMYs-IRES-Puro Retroviral Vector

RTV-022 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-GFP/Puro Retroviral Vector

RTV-053 10 µg
EUR 717
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-EF1-Puro Retroviral Vector

RTV-060 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-Cas9-Puro Retroviral Vector

RTV-5106 100 µL
EUR 717

pBABE- Puro SV40 LT

PVT10529 2 ug
EUR 301

pBABE-Puro-Sam68 Plasmid

PVTB00471-4a 2 ug
EUR 356

pBABE-Puro-ARHGEF4 Plasmid

PVTB00766-4a 2 ug
EUR 356

pBABE-Puro-CNOT1 Plasmid

PVTB00869-2a 2 ug
EUR 356

pBABE-Puro-PPP2R5A Plasmid

PVTB01072-4a 2 ug
EUR 356

pBABE puro-EGFP Plasmid

PVTB80003-4a 2 ug
EUR 356

pBABE-Puro-HA-Brca1

PVT17834 2 ug
EUR 424

HA- HIF1alpha- wt- pBabe- puro

PVT10257 2 ug
EUR 301

pBABE-Puro-KIFAP3-HA Plasmid

PVTB01071-4b 2 ug
EUR 356

pBABE-Puro-AP-2 Plasmid

PVTB01073-4a 2 ug
EUR 356

pBABE-puro mCherry-EGFP-LC3B

PVT14018 2 ug
EUR 911

pBABE-Puro-hTID-1 Plasmid

PVTB00190-4a 2 ug
EUR 356

pMXs-miRNA-GFP/Puro Retroviral Expression Vector

RTV-017 10 ?g
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs Retroviral Vector

RTV-010 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMYs Retroviral Vector

RTV-020 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMZs Retroviral Vector

RTV-030 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

hTERT (CMV, GFP-Puro) lentivirus

LVP1130-GP 1x107 IFU/ml x 200ul
EUR 349
Description: Premade lentivirus expressing human TERT gene under suCMV promoter, containing GFP-Puromycin fusion dual marker.

hTERT (CMV, RFP-Puro) lentivirus

LVP1130-RP 1x107 IFU/ml x 200ul
EUR 349
Description: Premade lentivirus expressing human TERT gene under suCMV promoter, containing RFP-Puromycin marker.

hTERT (EF1a, GFP-Puro) lentivirus

LVP1131-GP 1x107 IFU/ml x 200ul
EUR 349
Description: Premade lentivirus expressing human TERT gene under EF1a promoter, containing GFP-Puromycin fusion dual marker.

hTERT (EF1a, RFP-Puro) lentivirus

LVP1131-RP 1x107 IFU/ml x 200ul
EUR 349
Description: Premade lentivirus expressing human TERT gene under EF1a promoter, containing RFP-Puromycin marker.

pBABE-Puro-IQGAP1(1503-1657aa) Plasmid

PVTB01069-4a 2 ug
EUR 356

pBABE-Puro-Striatin(366-731aa) Plasmid

PVTB01070-4a 2 ug
EUR 356

pBABE-Puro-KIFAP3(606-772aa) Plasmid

PVTB01071-4a 2 ug
EUR 356

pBABE-Puro-AMER1(716-834aa) Plasmid

PVTB01079-4a 2 ug
EUR 356

pBABE- hLin28B

PVT10399 2 ug
EUR 301

pBABE GFP

PVT11055 2 ug
EUR 266

HEK293-TetR (Puro)

SC005-Puro 2 x 106 cell/ml x 1ml
EUR 1210
Description: tetracycline repressor in HEK293 stable cell line with Puromycin fusion marker

pWZL-Neo Retroviral Vector

RTV-001-NEO 10 ?g
EUR 566
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-Neo Retroviral Vector

RTV-011 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMX-GFP Retroviral Vector

RTV-050 10 µg
EUR 717
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMCs-GFP Retroviral Vector

RTV-051 10 µg
EUR 717
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMYs-GFP Retroviral Vector

RTV-052 10 µg
EUR 717
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-EF1? Retroviral Vector

RTV-063 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-CAG Retroviral Vector

RTV-064 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-CMV Retroviral Vector

RTV-065 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-SR? Retroviral Vector

RTV-066 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

rtTA (Puro) , Lentiviral particles

LVP400-Puro 1x107 IFU/ml x 200ul
EUR 404
Description: Pre-made lentiviral particles expressing reverse tetracycline Transcriptional Activator (rtTA) under enhanced EF1a promoter with Puromycin antibioic marker, provided in DMEM medium with 10% FBS.

hTERT Antibody

20-abx120550
  • EUR 328.00
  • EUR 105.00
  • EUR 133.00
  • 100 ug
  • 10 ug
  • 25 ug
  • Shipped within 1-3 working days.

hTERT Antibody

abx122247-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

hTERT Peptide

20-abx069990
  • EUR 182.00
  • EUR 84.00
  • 125 ul
  • 25 ul
  • Shipped within 1-3 working days.

Adeno-hTERT

G205 1.0 ml
EUR 1014

pBABE- neo- largeTcDNA

PVT11100 2 ug
EUR 301

pBABE-Hygro-3

PVT17647 2 ug
EUR 258

pBabe EGFR(T790M)

PVT17710 2 ug
EUR 341

pBabe EGFR Del1

PVT17718 2 ug
EUR 341

CMV-TetR (Puro) Lentiviral particles 

LVP017-Puro 1x107 IFU/ml x 200ul
EUR 404
Description: Pre-made lentiviral particles expressing tetracycline regulator protein (TetR) under CMV promoter, with Puromycin antibiotic marker.

β-Lactamase (Puro) lentiviral particles

LVP335-Puro 1x107 IFU/ml x 200ul
EUR 349
Description: pre-made lentiviral particles expressing β-Lactamase gene. A puromycin marker was expressed under RSV promoter. Particles is provided in DMEM medium with 10% FBS and 60ug/ml of polybrene.

EF1a-TetR (Puro) Lentiviral particles 

LVP459-Puro 1x107 IFU/ml x 200ul
EUR 404
Description: Pre-made lentiviral particles expressing tetracycline regulator protein (TetR) under enhanced EF1a promoter with Puromycin antibioic marker.

Hela-TetR (Puro) stable cells

SC035-Puro 2 x 106 cell/ml x 1ml
EUR 1210
Description: tetracycline repressor expression Hela stable cell line with Puromycin marker

Lenti-CMV-hTERT-RFP-2A-Puro Virus

LV625 10 ml
EUR 1059

Lenti-CMV-hTERT-GFP-2A-Puro Virus

LV623 10 ml
EUR 1059

hTERT (CMV, GFP-Puro) lentivirus in PBS

LVP1130-GP-PBS 1x108 IFU/ml x 200ul
EUR 710
Description: Concentrated lentivirus in PBS, expressing human TERT gene under suCMV promoter, containing GFP-Puromycin fusion dual marker.

hTERT (CMV, RFP-Puro) lentivirus in PBS

LVP1130-RP-PBS 1x108 IFU/ml x 200ul
EUR 710
Description: Concentrated lentivirus in PBS, expressing human TERT gene under suCMV promoter, containing RFP-Puromycin marker.

hTERT (EF1a, GFP-Puro) lentivirus in PBS

LVP1131-GP-PBS 1x108 IFU/ml x 200ul
EUR 710
Description: Concentrated lentivirus in PBS, expressing human TERT gene under EF1a promoter, containing GFP-Puromycin fusion dual marker.

hTERT (EF1a, RFP-Puro) lentivirus in PBS

LVP1131-RP-PBS 1x108 IFU/ml x 200ul
EUR 710
Description: Concentrated lentivirus in PBS, expressing human TERT gene under EF1a promoter, containing RFP-Puromycin marker.

LoxP GFP/RFP ColorSwitch (Puro) lentivirus

LVP460-Puro 1x107 IFU/ml x 200ul
EUR 710
Description: Pre-made lentiviral particles expressing "LoxP-GFP-stop-LoxP-RFP-Stop" cassette under suCMV promoter. It also contains a puromycin antibiotic selection marker under Rsv promoter. Virus is provided in DMEM medium with 10% FBS and 60ug/ml of polybrene.

pMXs-IRES-GFP Retroviral Vector

RTV-013 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-IRES-Neo Retroviral Vector

RTV-015 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-IRES-Bsd Retroviral Vector

RTV-016 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMYs-IRES-GFP Retroviral Vector

RTV-021 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMYs-IRES-Neo Retroviral Vector

RTV-023 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMCs-IRES-GFP Retroviral Vector

RTV-040 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-EF1-GFP Retroviral Vector

RTV-061 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMXs-EF1-Bsd Retroviral Vector

RTV-062 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pBABEpuro-Ras V12 Retroviral Vector

RTV-101 100 µL
EUR 717
Description: Use this gene-specific construct for downstream recombinant retroviral packaging

pBABEpuro-myr-Rac1 Retroviral Vector

RTV-201 100 µL
EUR 717
Description: Use this gene-specific construct for downstream recombinant retroviral packaging

pBABEhygro-Rac1 V12 Retroviral Vector

RTV-202 100 µL
EUR 717
Description: Use this gene-specific construct for downstream recombinant retroviral packaging

pBABEhygro-Cdc42 L61 Retroviral Vector

RTV-203 100 µL
EUR 717
Description: Use this gene-specific construct for downstream recombinant retroviral packaging

pBABEhygro-RhoA L63 Retroviral Vector

RTV-204 100 µL
EUR 717
Description: Use this gene-specific construct for downstream recombinant retroviral packaging

pBABEpuro-K-Ras Retroviral Vector

RTV-220 100 µL
EUR 717
Description: Use this gene-specific construct for downstream recombinant retroviral packaging

pMXs-GFP-LC3 Retroviral Vector

RTV-801 10 ?g
EUR 1169
Description: Expression vector contains a fusion of GFP and LC3. A separate GFP control vector is also included.

pCMV-VSV-G Retroviral Vector

RV-110 10 ?g
EUR 717
Description: Use this vector along with a packaging cell line and a cloning / expression vector for retroviral production.

pCMV-Gag-Pol Retroviral Vector

RV-111 10 ?g
EUR 717
Description: Use this vector along with a packaging cell line and a cloning / expression vector for retroviral production.

SV40 large T-antigen (Puro), CMV lentiviral particles

LVP016-Puro 1x107 IFU/ml x 200ul
EUR 349
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing puromycin marker.

SV40 large T-antigen (Puro), EF1a lentiviral particles

LVP557-Puro 1x107 IFU/ml x 200ul
EUR 349
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing puromycin marker.

MDA-MB-231 / GFP (Puro) Stable Cell Line

SC040-Puro 2 x 106 cell/ml x 1ml
EUR 1210
Description: GFP expression stable cell line in MDA-MB-231 cells with Puromycin resistance

MDA-MB-231 / Luciferase (Puro) Stable Cell Line

SC059-Puro 2 x 106 cell/ml x 1ml
EUR 1500
Description: Luciferase (firefly) expression stable cell line in MDA-MB-231 cells with Puromycin resistance

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